The comorbidity of chronic pain and opioid addiction is a serious problem that has been growing with the practice of prescribing opioids for chronic pain. Neuroimaging research has shown that chronic pain and opioid dependence both affect brain structure and function, but this is the first study to evaluate the neurophysiological alterations in patients with comorbid chronic pain and addiction. Eighteen participants with chronic low back pain and opioid addiction were compared with eighteen age- and sex-matched healthy individuals in a (...) pain-induction fMRI task. Unified structural equation modeling (SEM) with Lagrange multiplier (LM) testing yielded a network model of pain processing for patient and control groups based on 19 a priori defined regions. Tests of differences between groups on specific regression parameters were determined on a path-by-path basis using z-tests corrected for the number of comparisons. Patients with the chronic pain and addiction comorbidity had increased connection strengths; many of these connections were interhemispheric and spanned regions involved in sensory, affective, and cognitive processes. The affected regions included those that are commonly altered in chronic pain or addiction alone, indicating that this comorbidity manifests with neurological symptoms of both disorders. Understanding the neural mechanisms involved in the comorbidity is crucial to finding a comprehensive treatment, rather than treating the symptoms individually. (shrink)

Annotation A scholarly edition of a work by Adam Smith. The edition presents an authoritative text, together with an introduction, commentary notes, and scholarly apparatus.

Cancer and its treatment pose challenges that affect not only patients but also their significant others, including intimate partners. Accumulating evidence suggests that couples’ ability to communicate effectively plays a major role in the psychological adjustment of both individuals and the quality of their relationship. Two key conceptual models have been proposed to account for how couple communication impacts psychological and relationship adjustment: the social-cognitive processing (SCP) model and the relationship intimacy (RI) model. These models posit different mechanisms and outcomes, (...) and thus have different implications for intervention. The purpose of this project is to test and compare the utility of these models using comprehensive and methodologically rigorous methods. Aims are: (1) to examine the overall fit of the SCP and RI models in explaining patient and partner psychological and relationship adjustment as they occur on a day-to-day basis and over the course of 1 year; (2) to examine the fit of the models for different subgroups (males vs. females, and patients vs. partners); and (3) to examine the utility of various methods of assessing communication by examining the degree to which baseline indices from different measurement strategies predict self-reported adjustment at 1-year follow up. The study employs a longitudinal, multi-method approach to examining communication processes including: standard self-report questionnaires assessing process and outcome variables collected quarterly over the course of 1 year; smartphone-based ecological momentary assessments to sample participant reports in real time; and laboratory-based couple conversations from which we derive observational measures of communicative behavior and affective expression, as well as vocal indices of emotional arousal. Participants are patients with stage II-IV breast, colon, rectal, or lung cancer and their spouses/partners, recruited from two NCI-designated comprehensive cancer centers. Results will be published in scientific journals, presented at scientific conferences, and conveyed to a larger audience through infographics and social media outlets. Findings will inform theory, measurement, and the design and implementation of efficacious interventions aimed at optimizing both patient and partner well-being. (shrink)

Female coital orgasm may be an adaptation for preferentially retaining the sperm of males with “good genes.” One indicator of good genes may be physical attractiveness. Accordingly, R. Thornhill, S. W. Gangestad, and R. Comer (1995) found that women mated to more attractive men reported an orgasm during a greater proportion of copulations than did women mated to less attractive men. The current research replicates this finding, with several design variations. We collected self-report data from 388 women residing in the (...) United States or in Germany. Results support the hypothesis that women mated to more attractive men are more likely to report an orgasm at the most recent copulation than are women mated to less attractive men, after statistically controlling for several key variables. Discussion addresses (a) the inability of the present research to specify the causal link between female orgasm and male attractiveness and (b) the proactive nature of female sexuality documented in recent research guided by an evolutionary perspective. (shrink)

Books Reviewed in this Article: Theological Investigations, Vol. XVIII: God and Revelation. By Karl Rahner. Pp.vi, 304, London, Darton, Longman and Todd, 1984, £18.50. Theological Investigations, Volume XIX: Faith and Ministry. By Karl Rahner. Pp.vi, 282, London, Darton, Longman & Todd, 1984, £18.50. Theological Investigations: Volume XX: Concern for the Church. By Karl Rahner. Pp.vi, 191, London, Darton, Longman & Todd, 1981, £14.50. Concise Theological Dictionary. Edited by Karl Rahner and Herbert Vorgrimler. Pp.541, London, Burns & Oates, (...) 1983, £12.50. A New Dictionary of Christian Theology. Edited by Alan Richardson and John Bowden. Pp.xvii, 614, London, SCM Press, 1983, £19.50. The God of Forgiveness and Healing in the Theology of Karl Rahner. By J.N. King, Pp.93, Washington, University Press of America, 1982, $17.50, $6.75. In Search of Humanity, A Theological and Philosophical Approach. By John Macquarrie. Pp.vii, 280, London, SCM Press, 1982, £8.50. Faith and the Mystery of God. By Maurice Wiles. Pp.viii, 146, London, SCM Press, 1982, £4.50. Trinity and Temporality: The Christian Doctrine of God in the Light of Process Theology and the Theology of Hope. By John J. O'Donnell. Pp.xii, 215, Oxford University Press, 1983, £15.00. The Cosmic Christ in Origen and Teilhard de Chardin: A comparative Study. By James A. Lyons and edited by Maurice Wiles. Pp.xii, 236, Oxford University Press, 1982, £13.50. Grounded in Love: Sacramental Theology in an Ecumenical Perspective. By Frans Josef van Beeck. Pp.x, 151, Washington, University Press of America, 1982, $19.50, $9.25. Justification: The Author's First Book reissued with a New Introductory Chapter and the Original Response of Karl Barth. By Hans Küng. Pp.xlvi, 332, London, Burns and Oates, 1982, no price given. Reality and Evangelical Theology. By T.F. Torrance. Pp.174, Philadelphia, Westminster Press, 1982, $8.95. The Quest for the Historical Israel: Reconstructing Israel's Early History. By George W. Ramsey. Pp.xiv, 193, London, SCM Press, 1982, £5.50. Cantico del Cantici: Interpretatio Ludica. By Enrica Salvaneschi. Pp.140. Genoa, II Melangolo, 1982, 15, 000 Lire. Love Lyrics from the Bible: A Translation and Literary Study of the Song of Songs. By Marcia Falk. Pp.142, Sheffield, Almond Press, 1982, £14.95, £5.95. Old Testament Wisdom: An Introduction. By James L. Crenshaw. Pp.286, London, SCM Press, 1982, £5.95. The Sciences and Theology. Edited by A.R. Peacocke. Pp.xviii, 309, Stocksfield, Oriel Press, 1982, £14.00. Vision and Character: A Christian Educator's Alternative to Kohlberg. By C.R. Dykstra. Pp.viii, 160, Leominster, Fowler Wright Books, 1981, £4.45. Aristotle's Eudemian Ethics, Books I, II & III. Translated with a commentary by Michael Woods. Pp.xii, 234, Oxford, Clarendon Press: Oxford University Press, 1982, £11.50. Kant's Theory of Mind: An Analysis of the Paralogisms of Pure Reason. By Karl Ameriks. Pp.ix, 314, Oxford, Clarendon Press, 1982, £15.00. Heidegger's‘Being and Time’and the Possibility of Political Philosophy. By Mark Blitz. Pp.260, Ithaca, Cornell University Press, 1981, £13.75. Symbol as Sense: New Approaches to the Analysis of Meaning. Edited by Mary Le Cron Foster and Stanley H. Brandes. Pp.xvi, 416, New York, Academic Press, 1980, £19.60. The God Within. By Harry R. Klocker. Pp.x, 147, Washington, University Press of America, 1982, $19.00, $9.25. The Philosophical Frontiers of Christian Theology: Essays Presented to D.M. MacKinnon. Edited by Brian Hebblethwaite and Stewart Sutherland. Pp.ix, 252, Cambridge University Press, 1982, £17.50. Jews, Pagans and Christians in Conflict. By David Rokeah. Pp.232, Jerusalem, The Magnes Press, The Hebrew University, Leiden; E.J. Brill, 1982, 94 gld. Religion, Law, and the Growth of Constitutional Thought 1150–1650. By Brian Tierney. Pp.xi, 114, Cambridge University Press, 1982, £12.50. St John of the Cross: The Life and Thought of a Christian Mystic. By Alain Cugno. Pp.vi, 153, London, Burns & Oates, 1982, £6.95. Meister Eckhart: The Essential Sermons, Commentaries, Treatises and Defense. Translated by Edmund Colledge and Bernard McGinn. Pp.xviii, 360, London, SPCK, 1981, £8.50. Francisco de Osuna: the Third Spiritual Alphabet. Translated by May E. Giles. Pp.xvi, 624, London, SPCK, 1981, £12.50. Rome and the Anglicans. Edited with a Postscript by Wolfgang Haase. Pp.301, Berlin, Walter de Gruyter, 1982, 138 DM. The Westminster Confession in the Church today: Papers Prepared for the Church of Scotland Panel on Doctrine. Edited by Alasdair I.C. Heron. Pp.vii, 154, Edinburgh, Saint Andrew Press, 1982, £4.00. Essaying Montaigne: A Study of the Renaissance Institution of Writing and Reading. By John O'Neill, Pp.ix, 244, London, Routledge and Kegan Paul, 1982, £12.50. Rousseau after 200 years: Proceedings of the Cambridge Bicentennial Colloquium. Edited by R.A. Leigh. Pp.xv, 299, Cambridge University Press, 1982, £30.00 An American Experience of God: The Spirituality of Isaac Hecker. By John Farina. Pp.xii, 217, New York, Paulist Press, 1981, $11.95. Hecker Studies: Essays on the Thought of Isaac Hecker. Edited by John Farina. Pp.vii, 243, New York, Paulist Press, 1983, $6.95. (shrink)

The political writings of Kant and of Hegel present two contrasts, whose connection and explanation have never been adequately explored. The first contrast is in respect of the quality of their discussions of ‘home’ politics—in Kant's language, the ‘problem of establishing a perfect civic constitution’. Here Hegel shines. However much one may dislike the tone of voice, the vocabulary, the style and the arrangement of its arguments, his Philosophy of Right , especially when supplemented by his more topical political writings, (...) presents an array of dicta, judgments and arguments of notable penetration, balance and prescience. Consider for instance his account of the very different political functions of free associations and of representative bodies, and his perception of the symbolic—but crucially symbolic—role of head of state. On these, as on many other issues, Hegel's views deserve the credit that has of late begun to be restored to them. Whatever his philosophical failings, he had a remarkable sense of the key junctures of different strands in the life of politics; so that, although the kind of state he describes and admires retains little practical relevance today, his exposition of it remains a valuable training-ground in political appreciation. By contrast Kant's philosophy of the state, as we find it in Part II of his Philosophy of Right , in Part II of Theory and Practice and in Appendices I and II of Perpetual Peace , is at first sight little more than an academic exercise. It amounts to a restatement, in dehistoricized terms and in accordance with Kant's rationalist theory of morals, of Rousseau's central political teachings, viz. that an original, unanimous, unrescindable contract explains political allegiance, and that the idea of a General Will is a sufficient criterion of political justice within the state. From these two basic positions Kant develops a theory of civic obedience far more restrictive than that of Rousseau or indeed than that of Hobbes. Throughout, Kant accepts—in the spirit which one might accord to revelation—Rousseau's assumptions that government can be confined to issues that fall under a General Will, and that such a Will can be ‘found’ for the resolution of every political issue, so that honest men need never disagree about what the General Will is. But to say this is to say that Kant's concern with home politics is little more than academic. (shrink)

As I had rejected en bloc references to Bacchanalia as indications of date, it was a mere chance which led me, after the above had left my hands, to look up Cas. 980 ‘ nunc Bacchae nullae ludunt,’ quoted in Schanz, R. Lit.3, p. 78. As this affords an excellent opportunity of testing my conclusions, perhaps a word or two will not be out of place.

Designed to complement the editors' earlier selection, The Social and Political Philosophy of Jacques Maritain, this book arranges its material in six sections: theory of knowledge, metaphysics, ethics, esthetics, politics, and philosophy of history, with the editors contributing a one-page or two-page introduction to each section. The texts, taken from some fifteen of Maritain's works and in some cases published for the first time in English, are well chosen and interesting in themselves, but are too brief to present fully developed (...) arguments. This raises the question of the audience being aimed at. The book is not coherent enough to serve as a serious introduction to Maritain or to modern Thomism; it is rather a "sampler," and might be most useful as a kind of bedside book for those already acquainted with Maritain.--W. B. K. (shrink)

Is The Prelude a philosophical poem? It is, of course, many things besides: it is an autobiography; it contains profound reflections on psychology, education and politics; and there are passages of an almost purely lyrical character. Does it also contain philosophical poetry? On this question, the critics of Wordsworth are divided. Coleridge and Raleigh answer Yes; Arnold, Bradley, Dr. Leaves, from their different points of view, agree in answering No. I believe that the first answer is right, although it has (...) usually been supported by the wrong reasons. I believe the second answer to be wrong, although many of the arguments that are supposed to lead to it are in themselves sound enough. Those who say that The Prelude is not a philosophical poem, usually mean that it does not offer a coherent system of philosophy—that it expresses an original outlook and a personal wisdom, but that the only systematic philosophy in it comes at second-hand from Hartley or Coleridge and contributes not at all to the poem. And this is largely true. But the mistake is, to identify philosophy with system, philosophizing with “a philosophy.” This is a mistake that has been repudiated again and again by many of the greatest philosophers, from Socrates and Plato to Locke and Kant and others. I shall argue that The Prelude achieves philosophical poetry, because in it Wordsworth grapples with philosophical problems—problems which arise out of the story of his own early life—which are actually forced upon him by the poem itself; and because he tries to answer these problems in a way which would be possible only in poetry. (shrink)

Principled discussions of civil rights became inherently less likely as a direct result of the observation by Earl Warren, in Brown v. Board of Education, that, respecting freedmen, “Education of Negroes was almost non-existent, and practically all of the race were illiterate,” and in proportion as that observation increasingly became the foundation of common opinion on the subject. Warren's observation was not true in any meaningful or non-trivial sense. Nevertheless, it served to perpetuate the myth of a backward people needing (...) help to catch up instead of the truth of a people being held back. That is the perspective – the disadvantaged group perspective – that ultimately infected all discussion of civil rights, even after the designation of so-called “disadvantaged groups” had been extended beyond American blacks. To define civil rights, we may well begin with what all mankind would likely recognize. Thus the dictionary definition of “civil rights” stands: “the rights that belong to all individuals in a nation or community touching property, marriage, and the like.” In that definition the term “rights” may be further expanded to mean “legitimate claims,” following the definition of right as law – as “a claim or title or interest in anything whatever that is enforceable by law.” This definition applies with minimal distinction of regimes intruding and, therefore, without the host of recent complications in the United States that create the impression that civil rights have something to do with pluralism. Previously, the generic definition was thought to exhaust the meaning of the term in the United States. (shrink)

In this issue of the American Journal of Bioethics, manuscripts focus on the obligations of clinicians and researchers in pragmatic clinical trials (Garland, Morain, and Sugarman 2023; Morain and L...

"The drama Nietzsche has written is for the future Greeks." This somber note is the tonic both for the major and minor elements of Alderman’s Nietzsche’s Gift. The "drama" refers to Also Sprach Zarathustra, the central text in Alderman’s interpretation. The intention of placing Nietzsche centrally in the stream of philosophic creation is the minor theme.

This historical study of the responses that man has tried to give to the problem of death-"If I must some day die, what can I do to satisfy my desire to live?" as defined by Fr. Dunne—is occasionally turgid but more often provocative and enlightening. From the dawn of history in Mesopotamia to the present, the book investigates the political and literary consequences of different answers to this question and of different attitudes toward death in general. Although the book's organization (...) is chronological, it is explicitly oriented to contemporary concerns, with Nietzsche's statement that "God is dead" serving as a unifying leit-motif. The most rewarding sections are the discussions of Homer's epics and the analysis of the confusions between the right to life and the right over life that are traced from Calvin, Luther, Hobbes, and Rousseau to modern totalitarianism.—W. B. K. (shrink)

Margolis's main concern is to clarify aesthetic terminology, and especially to distinguish between normative and descriptive uses of such terms as "taste" and "aesthetic." His own definition of a work of art, however, "an artifact considered with respect to its design," hardly improves on the definitions he criticizes. Some of the problems he discusses can be seen as versions of the One and the Many: e.g., the relation between a symphony and its different performances or between a poem and the (...) different interpretations it gives rise to. Among the more interesting chapters are those on figurative language and on "truth and reference in fiction."—W. B. K. (shrink)

Father Etcheverry examines four varieties of humanism: rationalist-idealist, existentialist, Marxist, and Christian. For each of the first three varieties he centers his analysis on one or two individuals: Leon Brunschvicg, Sartre and Camus, and Marx and Engels respectively. He writes as a committed Christian humanist, arguing that only a relationship with God enables man to become truly man. All other varieties of humanism prevent this full development by raising to absolute status one or another of man's essential properties—reason, liberty, matter, (...) sociability, etc.—and subordinating him too exclusively to that property alone.—W. B. K. (shrink)

(1983). The illustrations of birds in the Vatican manuscript of De arte venandi cum avibus of Frederick II. Annals of Science: Vol. 40, No. 6, pp. 597-634.

Allen begins with a general survey of "atheism and atheists" in the Renaissance, gives brief sketches of six individual "atheists"—Pomponazzi, Cardano, Vanini, Montaigne, Charron, Bodin—devotes chapters to rational theology against atheism and to reason and immorality, and closes with a portrait of the "atheist redeemed" in the person of the Earl of Rochester, the arch-rake of the Restoration who was converted during his final illness. He points out that during this period "atheist" usually meant no more than a person whose (...) theology did not agree fully with that of the name-caller, and that none of the thinkers he mentions merited the term in any strict sense. The book is a wide-ranging, erudite survey without much attempt at either analysis in depth or synthesis, but Allen's somewhat Voltairean point of view helps give it form.—W. B. K. (shrink)

Everyone knows the statement of Servius that Virgil was compelled by Augustus to alter the second half of the Fourth Georgic after the fall of Gallus, and that he substituted the story of Aristaeus for the laudes Galli. This statement, often doubted by older generations, has had such a remarkable success in recent years that anyone who ventures to impugn it must feel that he is pleading with a halter round his neck before a one-sided jury. It is notable, however, (...) that these jurors, though one-sided, are by no means united, save in their determination to uphold the credit of Servius. One group will assure us that the episode of Aristaeus shows obvious signs not only of haste but of immaturity, and they draw a pathetic picture of the grief-stricken Virgil, ordered to bring out a second edition minus the praises of his friend Gallus, and half-heartedly throwing together some bits of juvenile stuff which he happened to have handy. Others assure us that the tale of Aristaeus shows us a more mature Virgil, nearer to the Virgil of the Aeneid. But the Servians really cannot have it both ways. They must make up their minds in the one direction or in the other if they are to be taken seriously. They make it doubly difficult for us to take them seriously when they try to tell us what Servius meant—but of that more anon. The present paper is an attempt by a converted Servian to examine frankly the arguments which have been advanced in support of Servius. Most of these may be found in Skutsch, Aus Vergils Frühzeit, pp. 140–147. One is very reluctant to use disparaging words about an eminent scholar who has served the cause of learning in so many ways; but it can scarcely be denied that the work just mentioned, in spite of its ingenuity and enthusiasm, shows a lamentable lack of three great essentials—a judicial temper, accurate statement of facts, and cogent reasoning. There is also at times a regrettable vagueness of expression, suggesting that the author is concealing inward doubts or shrinking from thought. All these deficiencies are to some extent present in the section with which this paper is concerned. (shrink)